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[Efficiency of polysaccharide translam for early treatment of acute radiation illness].

Authors :
Chertkov KS
Davydova SA
Nesterova TA
Zviagintseva TN
Eliakova LA
Source :
Radiatsionnaia biologiia, radioecologiia [Radiats Biol Radioecol] 1999 Sep-Oct; Vol. 39 (5), pp. 572-7.
Publication Year :
1999

Abstract

Antiradiation therapeutic efficiency of translam (1-->3; 1-->6-beta-D-glucan) produced by enzymatic synthesis out of laminarin, polysaccharide of Laminaria cychorioides, has been studied in four animal species (mice, guinea-pigs, dogs, monkeys). A stable curative effect has been observed following its administration within first 24 h after radiation exposure at doses that cause acute radiation sickness (about LD90). The preparation is nontoxic and has a broad therapeutic range which permits its practical application.

Details

Language :
Russian
ISSN :
0869-8031
Volume :
39
Issue :
5
Database :
MEDLINE
Journal :
Radiatsionnaia biologiia, radioecologiia
Publication Type :
Academic Journal
Accession number :
10576030