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Y-chromosomal DNA haplotype differences in control and infertile Italian subpopulations.
- Source :
-
European journal of human genetics : EJHG [Eur J Hum Genet] 1999 Sep; Vol. 7 (6), pp. 733-6. - Publication Year :
- 1999
-
Abstract
- Y-chromosomal DNA haplotypes were determined in 74 infertile and 216 control Italian males using eight biallelic markers. A significant difference in haplotype frequency was found, but could be explained by the geographical origins of the samples. The Y chromosome is thus a sensitive marker for population substructuring and may be useful for determining whether two population samples come from a single population, for example in association studies.
Details
- Language :
- English
- ISSN :
- 1018-4813
- Volume :
- 7
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- European journal of human genetics : EJHG
- Publication Type :
- Academic Journal
- Accession number :
- 10482965
- Full Text :
- https://doi.org/10.1038/sj.ejhg.5200359