Teratogenic evaluation of oxacillin.

Teratogenic studies of oxacillin in humans have not been published. The population-based data-set of the Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980-1996 contains 22,865 foetuses or newborns with congenital abnormalities and 38,151 matched control newborns without congenital abnormalities. The mothers of 14 cases and 19 controls were treated with oral oxacillin during pregnancy. A teratogenic risk of oxacillin was not detected in this case-control study.