[The characteristics of the pathogenesis and clinical forms of the course of glomerulonephritis in adolescent patients].

Overall, 138 patients at teen age and youths were studied for the clinical course of their glomerulonephritis. In adolescence, the onset of glomerulonephritis presents as urinary syndrome with hematuria and nephrotic syndrome. Acute glomerulonephritis with hematuria is accompanied by a low level of proteinuria and slow progression. Apparent benefit from the treatment occurred in 73 +/- 5% of patients (complete and partial clinical and laboratory remission), unsatisfactory results of treatment were recorded in 27 +/- 5% of patients. Persistence of nephrotic syndrome in patients demonstrating unsatisfactory results of treatment coincide with far greater frequency of unfavourable morphological forms of glomerulonephritis (mesangiocapillary and focal-segmentary glomerulosclerosis (hyalinosis), changes in canaliculi and interstitium, with loss of the functional reserves of the kidneys and effect of plasmapheresis on hyperlipidemia being recordable.