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Case-series investigation of intracranial neoplasms at a petrochemical research facility.
- Source :
-
American journal of industrial medicine [Am J Ind Med] 1999 Oct; Vol. 36 (4), pp. 450-8. - Publication Year :
- 1999
-
Abstract
- Background: From 1970 through 1997, 17 intracranial neoplasms were identified among 6,800 employees of a petrochemical research facility. This investigation describes the case-series.<br />Methods: The intracranial neoplasms were identified by self reports and record linkages, and were confirmed by medical records and a pathology review. Standardized incidence ratios (SIRs) compare observed and expected numbers of cases according to certain work characteristics.<br />Results: Overall, there were 17 observed and 10.5 expected intracranial neoplasms, including 11/4.7 benign intracranial tumors and 6/5.9 brain cancers. All brain cancers occurred among male research scientists or technicians. Four had worked at some time on the same floor of one building (SIR=12.6, 95% CI=3.4-32.1), and several had worked on a research project with at least one other brain cancer case. The benign intracranial neoplasm cases did not have common building assignments or work activities.<br />Conclusions: The occurrence pattern of brain cancers, but not that of benign tumors, suggests a possible occupational etiology.<br /> (Copyright 1999 Wiley-Liss, Inc.)
- Subjects :
- Adenoma epidemiology
Adult
Aged
Aged, 80 and over
Chicago epidemiology
Confidence Intervals
Cranial Nerve Neoplasms epidemiology
Female
Follow-Up Studies
Humans
Incidence
Male
Meningioma epidemiology
Middle Aged
Neurilemmoma epidemiology
Pituitary Neoplasms epidemiology
Research
Sex Factors
Vestibular Nerve
Brain Neoplasms epidemiology
Chemical Industry
Occupational Exposure
Petroleum adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0271-3586
- Volume :
- 36
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- American journal of industrial medicine
- Publication Type :
- Academic Journal
- Accession number :
- 10470010
- Full Text :
- https://doi.org/10.1002/(sici)1097-0274(199910)36:4<450::aid-ajim6>3.0.co;2-7