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Airway patterning: A paradigm for restricted signalling.
- Source :
-
Current biology : CB [Curr Biol] 1999 Jul 15; Vol. 9 (14), pp. R506-10. - Publication Year :
- 1999
-
Abstract
- Intercellular signalling is limited by the range of cell responsiveness, often mediated by repressors. A recently identified repressor, Sprouty, inhibits MAP kinase signalling in flies, mice and humans and has a conserved function in patterning the airways of these divergent species.
- Subjects :
- Animals
Drosophila
Epidermal Growth Factor genetics
Epidermal Growth Factor metabolism
Fibroblast Growth Factors genetics
Fibroblast Growth Factors metabolism
Lung embryology
MAP Kinase Signaling System
Mice
Mice, Knockout
Models, Biological
Drosophila Proteins
Insect Proteins physiology
Membrane Proteins
Signal Transduction
Trachea metabolism
Trachea physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0960-9822
- Volume :
- 9
- Issue :
- 14
- Database :
- MEDLINE
- Journal :
- Current biology : CB
- Publication Type :
- Academic Journal
- Accession number :
- 10421568
- Full Text :
- https://doi.org/10.1016/s0960-9822(99)80322-4