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A novel fast split-echo multi-shot diffusion-weighted MRI method using navigator echoes.

Authors :
Williams CF
Redpath TW
Norris DG
Source :
Magnetic resonance in medicine [Magn Reson Med] 1999 Apr; Vol. 41 (4), pp. 734-42.
Publication Year :
1999

Abstract

Difficulties in obtaining diffusion-weighted images of acceptable quality using conventional hardware and in a reasonable time have hindered the clinical application of diffusion-weighted magnetic resonance imaging (DWI). Diffusion-weighted fast spin-echo (FSE) sequences offer the possibility of fast DWI on standard hardware without the susceptibility problems associated with echoplanar imaging. However, motion in the presence of diffusion-sensitizing gradients can prevent fulfilment of the Meiboom Gill phase condition, leading to destructive interference between echo components and consequent signal losses. A recently proposed single-shot FSE sequence employed split-echo acquisition to address this problem. However, in a segmented FSE sequence, phase errors differ between successive echo trains, causing "ghosting" in the diffusion-weighted images that are not eliminated by split-echo acquistion alone. A DWI technique is presented that combines split-echo acquisition with navigator echo phase correction in a segmented FSE sequence. It is shown to be suitable for diffusion measurements in vivo using standard hardware.

Details

Language :
English
ISSN :
0740-3194
Volume :
41
Issue :
4
Database :
MEDLINE
Journal :
Magnetic resonance in medicine
Publication Type :
Academic Journal
Accession number :
10332849
Full Text :
https://doi.org/10.1002/(sici)1522-2594(199904)41:4<734::aid-mrm12>3.0.co;2-3