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Multi-component methodologies in solid-phase organic synthesis.
- Source :
-
Current medicinal chemistry [Curr Med Chem] 1999 Mar; Vol. 6 (3), pp. 255-70. - Publication Year :
- 1999
-
Abstract
- Solid-phase organic synthesis, particularly when used in conjunction with combinatorial techniques, is emerging as a revolutionary technology in chemistry. Multi-component reaction systems are particularly valued because several elements of diversity can be introduced in a single transformation thereby expanding the diversity of compound libraries. A variety of multi-component reactions have been successfully adapted for solid-phase technology as described in this review.
- Subjects :
- Cyclization
Chemistry, Organic methods
Technology, Pharmaceutical trends
Subjects
Details
- Language :
- English
- ISSN :
- 0929-8673
- Volume :
- 6
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Current medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 10219102