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[Severe flecainide acetate poisoning. Apropos of a case].
- Source :
-
Archives des maladies du coeur et des vaisseaux [Arch Mal Coeur Vaiss] 1999 Feb; Vol. 92 (2), pp. 273-7. - Publication Year :
- 1999
-
Abstract
- Poisoning with flecainide acetate is rare and associated with a high mortality. This usually occurs after massive ingestion but can also be observed during therapeutic overdose in patients with renal failure or with amiodarone therapy. The prognostic depends on the haemodynamic and rhythmic effects of the overdose one sign of which is widening of the QRS complexes. Major sodium bicarbonate or lactate infusion is the generally prescribed treatment. The authors report one case of a patient with renal failure on amiodarone who survived a severe flecainide acetate overdose.
- Subjects :
- Aged
Amiodarone administration & dosage
Amiodarone adverse effects
Anti-Arrhythmia Agents administration & dosage
Anti-Arrhythmia Agents adverse effects
Anti-Arrhythmia Agents pharmacokinetics
Atrial Flutter complications
Atrial Flutter drug therapy
Biological Availability
Calcium Gluconate therapeutic use
Charcoal therapeutic use
Combined Modality Therapy
Consciousness Disorders chemically induced
Diabetic Nephropathies therapy
Drug Interactions
Drug Therapy, Combination
Flecainide administration & dosage
Flecainide pharmacokinetics
Hemofiltration
Humans
Hypertension complications
Kidney Failure, Chronic therapy
Male
Poisoning drug therapy
Poisoning therapy
Renal Dialysis
Respiration, Artificial
Sodium Bicarbonate therapeutic use
Sodium Channel Blockers
Uremia chemically induced
Anti-Arrhythmia Agents poisoning
Diabetic Nephropathies complications
Flecainide poisoning
Heart Block chemically induced
Hypotension chemically induced
Intestinal Pseudo-Obstruction chemically induced
Kidney Failure, Chronic complications
Pulmonary Edema chemically induced
Subjects
Details
- Language :
- French
- ISSN :
- 0003-9683
- Volume :
- 92
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Archives des maladies du coeur et des vaisseaux
- Publication Type :
- Academic Journal
- Accession number :
- 10078349