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A murine model of renal abscess formation.
- Source :
-
Clinical and diagnostic laboratory immunology [Clin Diagn Lab Immunol] 1999 Mar; Vol. 6 (2), pp. 273-5. - Publication Year :
- 1999
-
Abstract
- We developed a murine model of kidney abscess by direct renal injection of either Escherichia coli (1 x 10(6) to 7 x 10(6) organisms) or sterile medium. Bacterial infection produced renal abscesses, bacteremia, and late-onset leukocytosis in all animals. Controls were unaffected. This model may be useful for the study of various sequelae of kidney infection.
- Subjects :
- Abscess immunology
Abscess physiopathology
Animals
Bacteremia immunology
Bacteremia microbiology
Bacteremia physiopathology
Escherichia coli Infections immunology
Female
Kidney Diseases immunology
Kidney Diseases physiopathology
Leukocytosis microbiology
Mice
Neutrophils microbiology
Abscess microbiology
Disease Models, Animal
Escherichia coli Infections physiopathology
Kidney Diseases microbiology
Mice, Inbred Strains
Subjects
Details
- Language :
- English
- ISSN :
- 1071-412X
- Volume :
- 6
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Clinical and diagnostic laboratory immunology
- Publication Type :
- Academic Journal
- Accession number :
- 10066667
- Full Text :
- https://doi.org/10.1128/CDLI.6.2.273-275.1999