Back to Search
Start Over
[Vertical HIV-I-transmission. I. Risk and prevention in pregnancy].
- Source :
-
Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 1998 Dec 12; Vol. 142 (50), pp. 2720-4. - Publication Year :
- 1998
-
Abstract
- Without anti-HIV treatment, mother to child HIV-I transmission occurs in 15-30% of HIV positive pregnancies. Transmission occurs mostly in the last trimester or at birth. The maternal virus load in the last trimester and around birth is strongly related to the risk of HIV transmission to the child. This risk can be reduced during pregnancy by anti-HIV treatment and in certain cases by performing a caesarean section. It is recommended to determine the plasma virus load several times during pregnancy. If the virus load is found to be high, measurement of plasma anti-HIV drug concentrations and anti-HIV drug resistance may prompt modification of the anti-HIV drug regimen with the objective of achieving maximal suppression of virus replication in the last trimester.
- Subjects :
- Adolescent
Adult
Antiviral Agents therapeutic use
CD4 Lymphocyte Count
Drug Therapy, Combination
Female
HIV Infections diagnosis
HIV Infections prevention & control
HIV-1 isolation & purification
Humans
Infant, Newborn
Maternal-Fetal Exchange
Pregnancy
Pregnancy Complications, Infectious diagnosis
Pregnancy Trimester, Third
Risk Assessment
Viral Load
HIV Infections transmission
HIV-1 pathogenicity
Infectious Disease Transmission, Vertical prevention & control
Pregnancy Complications, Infectious prevention & control
Prenatal Exposure Delayed Effects
Subjects
Details
- Language :
- Dutch; Flemish
- ISSN :
- 0028-2162
- Volume :
- 142
- Issue :
- 50
- Database :
- MEDLINE
- Journal :
- Nederlands tijdschrift voor geneeskunde
- Publication Type :
- Academic Journal
- Accession number :
- 10065235