Establishment of Pig Model for Common Bile Duct Repair.

Objectives To establish the model of common bile duct repair in pig and compare the acellular dermal with biliary intestinal anastomosis. Methods Common bile ducts were removed partly or completely, and then their common bile ducts were repaired by acellular dermal matrix (ADM), the repair effects were compared between the acellular dermal matrix and Biliary intestinal anastomosis. Results In 33 normal experiment pigs, 30 pigs survived over 2 weeks postoperation. The success rate of operation was 91%. The operation time of ADM group was obviously shorter than Biliary intestinal anastomosis group (P < 0.05). Median survival time of ADM group was obviously longer than Biliary intestinal anastomosis group (P < 0.05). Conclusion Shorter operation time, fewer complications and longer survival time all imply that the effect of ADM for repairing common bile duct is good. [ABSTRACT FROM AUTHOR]