Successful treatment of Cronkhite--Canada syndrome using anti-tumor necrosis factor antibody therapy.

The article describes the case of a 57-year-old man who suffered from alopecia, anorexia and severe diarrhea, apart from dystrophic nail changes and pigmentation on the hands, and was diagnosed to be suffering from Cronkhite-Canada syndrome (CCS), a rare nonhereditary syndrome described by gastrointestinal polyposis and ectodermal changes. It discusses how anti-tumor necrosis factor (TNF) therapy could help treat CCS. Colonoscopy images showing CCS before and after treatment are also presented.