Visceral Leishmaniasis Relapse in HIV Patients—A Role for Myeloid-Derived Suppressor Cells?

The article presents a study which examines the role of myeloid-derived suppressor cells (MDSC) in the immune suppression mechanisms in HIV patients with visceral leishmaniasis (VL). Findings reveal that MDSC could contribute partially to immune suppression associated to VL. It concludes that the role of MDSC in an HIV-VL coinfection model could represent a novel patho-immunological phenomenon about the diseases.