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Thermodynamically consistent orthotropic activation model capturing ventricular systolic wall thickening in cardiac electromechanics.
- Source :
-
European Journal of Mechanics A: Solids . Nov2014, Vol. 48, p129-142. 14p. - Publication Year :
- 2014
-
Abstract
- The complex phenomena underlying mechanical contraction of cardiac cells and their influence in the dynamics of ventricular contraction are extremely important in understanding the overall function of the heart. In this paper we generalize previous contributions on the active strain formulation and propose a new model for the excitation-contraction coupling process. We derive an evolution equation for the active fiber contraction based on configurational forces, which is thermodynamically consistent. Geometrically, we link microscopic and macroscopic deformations giving rise to an orthotropic contraction mechanism that is able to represent physiologically correct thickening of the ventricular wall. A series of numerical tests highlights the importance of considering orthotropic mechanical activation in the heart and illustrates the main features of the proposed model. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09977538
- Volume :
- 48
- Database :
- Academic Search Index
- Journal :
- European Journal of Mechanics A: Solids
- Publication Type :
- Academic Journal
- Accession number :
- 98143090
- Full Text :
- https://doi.org/10.1016/j.euromechsol.2013.10.009