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Computerized cognitive remediation training for schizophrenia: An open label, multi-site, multinational methodology study.
- Source :
-
Schizophrenia Research . Aug2012, Vol. 139 Issue 1-3, p87-91. 5p. - Publication Year :
- 2012
-
Abstract
- A recent single-site study (Fisher et al., 2009. Am J Psychiatry. 166 (7) 805–11) showed that repeated training with the Brain Fitness Program (BFP) improved performance on a battery of neuropsychological tasks. If replicated these data suggest an important non-pharmacological method for ameliorating cognitive impairment in schizophrenia. Our study evaluated the BFP training effects in an open-label, multi-site, multinational clinical trial. Fifty-five stable adult patients with schizophrenia on regular antipsychotic medication completed ≥ 32 BFP training sessions over 8–10 weeks. Training effects on cognitive performance and functional capacity outcome measures were measured using CogState® schizophrenia battery, UCSD Performance based Skills Assessment (UPSA-2) and Cognitive Assessment Interview (CAI). BFP training showed a large and significant treatment effect on a training exercise task (auditory processing speed), however this effect did not generalize to improved performance on independent CogState® assessment. There were no significant effects on UPSA-2 or CAI scores. Our study demonstrated the feasibility of implementing BFP training in a multi-site study. However, BFP training did not show significant treatment effects on cognitive performance or functional capacity outcome measures despite showing large and significant effects on a training exercise. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09209964
- Volume :
- 139
- Issue :
- 1-3
- Database :
- Academic Search Index
- Journal :
- Schizophrenia Research
- Publication Type :
- Academic Journal
- Accession number :
- 98141771
- Full Text :
- https://doi.org/10.1016/j.schres.2012.01.042