Iodine-promoted efficient synthesis of diheteroaryl thioethers via the integration of iodination/condensation/cyclization/dehydration sequences.

Authors :: Xue, Wei-jian
Li, Hong-zheng
Zheng, Kai-lu
Wu, An-xin
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Oct2014, Vol. 55 Issue 40, p5544-5547. 4p.
Publication Year :: 2014
Abstract: A novel method for the construction of diheteroaryl thioethers from aromatic methyl ketones and thiourea is described. Iodine is the unique catalyst in this protocol. The transformation is free of foul-smell thiols and transition metal. In addition, this method could synthesize two thiazole rings and a sulfur bridge in one pot. [ABSTRACT FROM AUTHOR]

Subjects :: *IODINE
*SULFIDES
*IODINATION
*RING formation (Chemistry)
*DEHYDRATION reactions
*METHYL ketones

Language :: English
ISSN :: 00404039
Volume :: 55
Issue :: 40
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 98140295
Full Text :: https://doi.org/10.1016/j.tetlet.2014.08.042

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