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Synthesis and biological evaluation of a new trioxaquine containing a trioxane moiety obtained by halogenocyclisation of a hemiperoxyacetal
- Source :
-
Comptes Rendus Chimie . Jan2003, Vol. 6 Issue 1, p153. 8p. - Publication Year :
- 2003
-
Abstract
- The preparation and the biological evaluation of a new antimalarial modular drug, named trioxaquine are reported. The trioxane moiety of this trioxaquine is prepared through the halogenocyclisation of a hemiperoxyacetal derived from the allylic hydroperoxide of 2,3-dimethyl-2-butene. [Copyright &y& Elsevier]
- Subjects :
- *ANTIMALARIALS
*ANTIPARASITIC agents
Subjects
Details
- Language :
- English
- ISSN :
- 16310748
- Volume :
- 6
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Comptes Rendus Chimie
- Publication Type :
- Academic Journal
- Accession number :
- 9791240
- Full Text :
- https://doi.org/10.1016/S1631-0748(03)00007-9