ChemInform Abstract: Regio- and Diastereoselective Construction of α-Hydroxy-δ-amino Ester Derivatives via 1,4-Conjugate Addition of β,γ-Unsaturated N-Sulfonylimines.

Authors :: Qiu, Lin
Gao, Lixin
Tang, Jixing
Wang, Dongwei
Guo, Xin
Liu, Shunying
Yang, Liping
Li, Jia
Hu, Wenhao
Source :: ChemInform. Sep2014, Vol. 45 Issue 38, pno-no. 1p.
Publication Year :: 2014
Abstract: The title compounds show inhibitory activity on PTP1B and SIRT1 enzymes in vitro. [ABSTRACT FROM AUTHOR]

Subjects :: *ENZYME inhibitors
*PHASE-transfer catalysis
*MICHAEL reaction
*ASYMMETRIC synthesis
*AMINE derivatives
*UNSATURATED compounds

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