A new and efficient one-pot synthesis of 2-hydroxy-1,4-dihydrobenzoxazines via a three-component Petasis reaction.

Authors :: Chouguiat, Louisa
Boulcina, Raouf
Carboni, Bertrand
Demonceau, Albert
Debache, Abdelmadjid
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Sep2014, Vol. 55 Issue 37, p5124-5128. 5p.
Publication Year :: 2014
Abstract: The secondary amines synthesized by the reaction between 2-aminophenols and aromatic aldehydes, via the reduction of the corresponding imines, were employed in the synthesis of new 2-hydroxy-2 H -1,4-benzoxazine derivatives through a one-pot Petasis multicomponent reaction in good to excellent yields. [ABSTRACT FROM AUTHOR]

Subjects :: *BENZOXAZINES
*CHEMICAL synthesis
*CHEMICAL reactions
*AROMATIC aldehydes
*IMINES
*CHEMICAL reduction
*AMINOPHENOLS

Language :: English
ISSN :: 00404039
Volume :: 55
Issue :: 37
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 97617010
Full Text :: https://doi.org/10.1016/j.tetlet.2014.07.093

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