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Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases.
- Source :
-
European Spine Journal . Aug2014, Vol. 23 Issue 8, p1791-1796. 6p. - Publication Year :
- 2014
-
Abstract
- Purpose: To assess whether perioperative allogenic blood transfusions in patients undergoing surgical treatment for spinal metastases independently influence patient survival. Methods: A retrospective study including 170 consecutive patients undergoing surgical treatment for spinal metastases in 2009 and 2010 at a tertiary referral center. Variables related to postoperative survival were all included in the same multivariable logistic regression analysis with either 3- or 12-month survival as the dependent variable. The independent variables were: transfusion of allogenic red blood cells, age at surgery, gender, preoperative hemoglobin, revised Tokuhashi score and no. of instrumented levels. Results: Perioperative allogenic blood transfusion of 1-2 units was associated with increased 12-month survival [ p = 0.049, odds ratio 2.619 (confidence interval 1.004-6.831)], but not with 3-month survival. Larger transfusion volumes did not significantly influence survival. Conclusion: The results of the present study support that perioperative blood transfusion of <5 units does not decrease survival in patients operated for spinal metastases. Transfusion of 1-2 units seems to be associated with increased 12-month survival. Future studies should assess if a liberal transfusion regime can be applied to this group of patients; thereby, prioritizing early postoperative mobilization. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09406719
- Volume :
- 23
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- European Spine Journal
- Publication Type :
- Academic Journal
- Accession number :
- 97252953
- Full Text :
- https://doi.org/10.1007/s00586-014-3330-y