Back to Search
Start Over
Synthesis of different isoindolone embedded heterocycles with phenolic subunits from a common intermediate, 3-(2'-hydroxyaroyl)-2,3-dihydroisoindol-1-ones.
- Source :
-
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry . Aug2014, Vol. 55 Issue 32, p4466-4474. 9p. - Publication Year :
- 2014
-
Abstract
- A series of biologically important isoindolone embedded heterocycles such as tetracyclic 2,4-diamino-5-aryl-10-oxo-10H-1,10a-diazaindeno[2,1-a]indene-3-carbonitriles and tricyclic 1-aryl-3,5-dioxo-1H-imidazo-[3,4-b]isoindoles have been synthesized from an easily derived common intermediate, 3-(2'-hydroxyaroyl)-2,3-dihydroisoindol-1-ones. The significant advantages of the present methodologies are the use of simple and easily available starting materials and reagents, operational simplicity, and good yields of the products with high atom-economy. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CHEMICAL synthesis
*HETEROCYCLIC compounds
*PHENOLS
*ISOINDOLE
*MICROWAVES
Subjects
Details
- Language :
- English
- ISSN :
- 00404039
- Volume :
- 55
- Issue :
- 32
- Database :
- Academic Search Index
- Journal :
- Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 97211967
- Full Text :
- https://doi.org/10.1016/j.tetlet.2014.06.064