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Overexpression of a truncated human topoisomerase III partially corrects multiple aspects of the...

Authors :
Fritz, Eberhard
Elsea, Sarah H.
Source :
Proceedings of the National Academy of Sciences of the United States of America. 04/29/97, Vol. 94 Issue 9, p4538. 5p. 1 Black and White Photograph, 1 Diagram, 3 Graphs.
Publication Year :
1997

Abstract

Postulates that topoisomerase III may be deregulated in A-T cells and that CAT4.5 complements the A-T phenotype via a dominant negative mechanism. Cell culture, survival and apoptosis assays; Northern blot analysis; Sequence analysis and comparisons.

Subjects

Subjects :
*ISOMERASES

Details

Language :
English
ISSN :
00278424
Volume :
94
Issue :
9
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
9710082446
Full Text :
https://doi.org/10.1073/pnas.94.9.4538