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Preparation of 4,5 disubstituted-2H-1,2,3-triazoles from (Z)-2,3-diaryl substituted acrylonitriles.

Authors :
Madadi, Nikhil Reddy
Penthala, Narsimha Reddy
Lin Song
Hendrickson, Howard P.
Crooks, Peter A.
Source :
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jul2014, Vol. 55 Issue 30, p4207-4211. 5p.
Publication Year :
2014

Abstract

2H-1,2,3-Triazoles (2) were synthesized by [3+2] cycloaddition of (Z)-2,3-diaryl substituted acrylonitriles (1) with sodium azide and ammonium chloride in DMF/water. This method represents a facile and efficient reaction procedure for the synthesis of 4,5-diaryl-2H-1,2,3-triazoles in modest to good yields. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00404039
Volume :
55
Issue :
30
Database :
Academic Search Index
Journal :
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :
Academic Journal
Accession number :
96978008
Full Text :
https://doi.org/10.1016/j.tetlet.2014.05.045