Back to Search
Start Over
Total Synthesis of Taiwaniadducts B, C and D.
- Source :
-
Journal of the American Chemical Society . 6/11/2014, Vol. 136 Issue 23, p8185-8188. 4p. - Publication Year :
- 2014
-
Abstract
- The first total syntheses of taiwaniadducts B, C, and D have been accomplished. Two diterpenoid segments were prepared with high enantiopurity, both through Ir-catalyzed asymmetric polyene cyclization. A sterically demanding intermolecular Diels-Alder reaction promoted by Er(fod)3 assembled the scaffold of taiwaniadducts B and C. A carbonyl-ene cyclization forged the cage motif of taiwaniadduct D at a late stage, providing over 200 mg of this compound. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 136
- Issue :
- 23
- Database :
- Academic Search Index
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- 96808151
- Full Text :
- https://doi.org/10.1021/ja503972p