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Anti-VEGF Therapy in Myopic Choroidal Neovascularization: Long-Term Results.
- Source :
-
Ophthalmologica . Jun2014, Vol. 232 Issue 1, p57-63. 7p. - Publication Year :
- 2014
-
Abstract
- Purpose: To evaluate the medium- and long-term efficacy of anti-VEGF agents in the treatment of choroidal neovascularization secondary to pathologic myopia (mCNV). Methods: We performed a retrospective analysis of patients with mCNV who had been treated with intravitreous anti-VEGF for at least 2 years. The best-corrected visual acuity (BCVA) and central retinal thickness (CRT) were compared before and after the treatment. The number of injections per year was also assessed. Results: The results were analysed at 2 years for 67 eyes, at 3 years for 52 eyes, at 4 years for 28 eyes and at 5 years for 13 eyes. The mean change from baseline BCVA was significant at 2 years (+8.6 letters; p < 0.001) and this gain remained significantly stable for a period of 5 years. The mean CRT showed a significant decrease over time, with a nadir at 2 years (-104.0 μm; p < 0.001). The mean number of injections performed during the first year was 5.2, being lower in subsequent years (p < 0.001). Conclusion: In this subset of patients with mCNV, an intravitreous therapy with anti-VEGF agents proved to have effective results over 5 years, with a sustained increase in BCVA. © 2014 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00303755
- Volume :
- 232
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Ophthalmologica
- Publication Type :
- Academic Journal
- Accession number :
- 96796008
- Full Text :
- https://doi.org/10.1159/000360307