Precision of the reportable result. Simultaneous optimisation of number of preparations and injections for sample and reference standard in quantitative liquid chromatography.

Highlights: [•] The precision of the final or reportable result can be optimised. [•] An equation is developed to optimise also the format of calibration. [•] Optimisation is possible by varying the number of determinations. [•] Reliable variances are the basis for optimisation. [•] Obtaining reliable variance contributions is the aim of precision studies. [ABSTRACT FROM AUTHOR]