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DNA metabolism: Bases of DNA repair and regulation.
- Source :
-
Nature Chemical Biology . Jul2014, Vol. 10 Issue 7, p487-488. 2p. - Publication Year :
- 2014
-
Abstract
- The article focuses on a study which demonstrates that that 5-hydroxymethyluracil (5hmU) can be produced by direct ten eleven translocation (Tet)-mediated oxidation of thymine bases in stem cell DNA. Topics discussed include spontaneous deamination of cytosine, regulatory roles of base modifications that are produced from thymine and 5hmU modifications resulting from thymine oxidation.
- Subjects :
- *DNA repair
*OXIDATION of DNA
*DNA metabolism
*THYMINE
*DEAMINATION
Subjects
Details
- Language :
- English
- ISSN :
- 15524450
- Volume :
- 10
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Nature Chemical Biology
- Publication Type :
- Academic Journal
- Accession number :
- 96582904
- Full Text :
- https://doi.org/10.1038/nchembio.1553