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A detailed three-step protocol for live imaging of intracellular traffic in polarized primary porcine RPE monolayers.

Authors :
Toops, Kimberly A.
Tan, Li Xuan
Lakkaraju, Aparna
Source :
Experimental Eye Research. Jul2014, Vol. 124, p74-85. 12p.
Publication Year :
2014

Abstract

Highlights: [•] We present a detailed 3-step protocol for live imaging of polarized primary RPE. [•] Step 1: a protocol for primary porcine retinal pigment epithelial culture. [•] This method results in highly polarized monolayers within 7 days. [•] Step 2: two gene delivery protocols that yield efficient transgene expression. [•] Step 3: High speed live imaging to visualize intracellular traffic in the RPE. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00144835
Volume :
124
Database :
Academic Search Index
Journal :
Experimental Eye Research
Publication Type :
Academic Journal
Accession number :
96582635
Full Text :
https://doi.org/10.1016/j.exer.2014.05.003