Quercetin mitigates lead acetate-induced behavioral and histological alterations via suppression of oxidative stress, Hsp-70, Bak and upregulation of Bcl-2.

Highlights: [•] Lead acetate (LA) induced motor and somatosensory impairments and oxidative stress. [•] LA have shown upregulation of Hsp-70 and Bak and downregulation of Bcl-2. [•] Quercetin successfully protected the histological architecture of brain. [•] Quercetin reduced the lead-induced oxidative stress and inhibited the apoptosis. [ABSTRACT FROM AUTHOR]