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The theory of bipolar disorder as an illness of accelerated aging: Implications for clinical care and research.

Authors :
Rizzo, Lucas Bortolotto
Costa, Leonardo Gazzi
Mansur, Rodrigo B.
Swardfager, Walter
Belangero, Síntia Iole
Grassi-Oliveira, Rodrigo
McIntyre, Roger S.
Bauer, Moisés E.
Brietzke, Elisa
Source :
Neuroscience & Biobehavioral Reviews. May2014, Vol. 42, p157-169. 13p.
Publication Year :
2014

Abstract

Highlights: [•] Pathophysiological changes observed in BD converge on a model of premature aging. [•] Individuals with BD present high rates of age related medical illnesses. [•] Dysregulation in immune system and neurotrophins are present in both conditions. [•] Recognition of BD as an accelerated aging disease opens a new avenue of investigation. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
01497634
Volume :
42
Database :
Academic Search Index
Journal :
Neuroscience & Biobehavioral Reviews
Publication Type :
Academic Journal
Accession number :
95827083
Full Text :
https://doi.org/10.1016/j.neubiorev.2014.02.004