Back to Search
Start Over
Poly(methacrylic acid) microparticles coated with nanolayered chitosan and carbon nanotubes via electrostatic self-assembly for gatifloxacin delivery.
- Source :
-
Materials Letters . Jun2014, Vol. 125, p198-201. 4p. - Publication Year :
- 2014
-
Abstract
- Abstract: A novel poly(methacrylic acid) (PMAA) microcarriers coated with nanolayered chitosan(Cs) and carboxyl modified multi-walled carbon nanotubes (MWCNTs-COOH) via self-assembly method, has been successfully prepared for better loading and sustained release of gatifloxacin (GFLX). Due to the multi-loading and gradient release properties, PMAA/Cs/CNTs could adsorb a great amount of drug (84.89±9.63μgmg−1), and 64.74±2.78% of its loading could slowly release in 24h, which is important to delivery GFLX effectively and to reduce the risk of side effects. [Copyright &y& Elsevier]
- Subjects :
- *POLYMETHACRYLIC acids
*CARBON nanotubes
*CHITOSAN
*PARTICLES
*DRUG delivery systems
Subjects
Details
- Language :
- English
- ISSN :
- 0167577X
- Volume :
- 125
- Database :
- Academic Search Index
- Journal :
- Materials Letters
- Publication Type :
- Academic Journal
- Accession number :
- 95825686
- Full Text :
- https://doi.org/10.1016/j.matlet.2014.03.079