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Combining glycocluster synthesis with protein engineering: an approach to probe into the significance of linker length in a tandem-repeat-type lectin (galectin-4).
- Source :
-
Carbohydrate Research . May2014, Vol. 389, p25-38. 14p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] Synthesis of glycoclusters presenting lactose and 2′-fucosyl lactose on different scaffolds. [•] Engineering of galectin-4 mutants to probe structure–activity relationships with glycoclusters. [•] The impact of structural alterations by combining application of glycoclusters and mutants. [Copyright &y& Elsevier]
- Subjects :
- *PROTEIN engineering
*LECTINS
*GALECTINS
*LACTOSE
*TISSUE scaffolds
*MUTANT proteins
Subjects
Details
- Language :
- English
- ISSN :
- 00086215
- Volume :
- 389
- Database :
- Academic Search Index
- Journal :
- Carbohydrate Research
- Publication Type :
- Academic Journal
- Accession number :
- 95723048
- Full Text :
- https://doi.org/10.1016/j.carres.2013.12.024