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Clinical impact of intra-aortic balloon pump during extracorporeal life support in patients with acute myocardial infarction complicated by cardiogenic shock.
- Source :
-
BMC Anesthesiology . 2014, Vol. 14 Issue 1, p72-84. 13p. - Publication Year :
- 2014
-
Abstract
- Background There is no available data on clinical outcome in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock who are supported by an intra-aortic balloon pump (IABP) in combination with extracorporeal life support (ECLS). Methods We analysed 96 consecutive patients with AMI and complicating cardiogenic shock who were assisted by an ECLS system between January 2004 and December 2011. The primary outcome was in-hospital mortality. The secondary outcomes were the success rate of weaning from ECLS and the lactate clearance for 48 hours (%). Results A combination of IABP and ECLS was used in 41 (42.7%) patients. In-hospital mortality occurred for 51 patients (ECLS with IABP versus ECLS alone; 51.2% vs. 54.5%, p = 0.747). The success rate of weaning from ECLS was similar between the two groups (63.4% vs. 58.2%, p = 0.604). Complications such as ischemia of a lower extremity or bleeding at the ECLS insertion site (p = 0.521 and p = 0.667, respectively) did not increase when ECLS was combined with IABP. Among patients who survived for 24 hours after intervention, lactate clearance was not significantly different between patients who received ECLS alone and those who received ECLS with IABP (p = 0.918). Conclusions The combined use of ECLS and IABP did not improve in-hospital survival in patients with AMI complicated by cardiogenic shock. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ARTIFICIAL blood circulation
*CARDIOGENIC shock
*CHI-squared test
*FISHER exact test
*HOSPITALS
*INTRA-aortic balloon counterpulsation
*LACTATES
*DEATH rate
*MYOCARDIAL infarction
*HEALTH outcome assessment
*PROBABILITY theory
*T-test (Statistics)
*U-statistics
*TREATMENT effectiveness
*DATA analysis software
*KAPLAN-Meier estimator
Subjects
Details
- Language :
- English
- ISSN :
- 14712253
- Volume :
- 14
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- BMC Anesthesiology
- Publication Type :
- Academic Journal
- Accession number :
- 95709056
- Full Text :
- https://doi.org/10.1186/1471-2253-14-27