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CDKN2B expression and subcutaneous adipose tissue expandability: Possible influence of the 9p21 atherosclerosis locus.
- Source :
-
Biochemical & Biophysical Research Communications . Apr2014, Vol. 446 Issue 4, p1126-1131. 6p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] The tumor suppressor gene CDKN2B is highly expressed in human adipose tissue. [•] Risk alleles at the 9p21 locus modify CDKN2B expression in a BMI-dependent fashion. [•] There is an inverse relationship between expression of CDKN2B and adipogenic genes. [•] CDKN2B expression influences to postprandial triacylglycerol clearance. [•] CDKN2B expression in adipose tissue is linked to markers of hepatic steatosis. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 446
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 95670719
- Full Text :
- https://doi.org/10.1016/j.bbrc.2014.03.075