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Sox11 promotes endogenous neurogenesis and locomotor recovery in mice spinal cord injury.

Authors :
Guo, Yuji
Liu, Shangming
Zhang, Xianghong
Wang, Liyan
Zhang, Xiaoli
Hao, Aijun
Han, Aiqing
Yang, Jie
Source :
Biochemical & Biophysical Research Communications. Apr2014, Vol. 446 Issue 4, p830-835. 6p.
Publication Year :
2014

Abstract

Highlights: [•] The expression of Sox11 is increased in the injured spinal cord after SCI. [•] Sox11 expression is located in NSCs and newly-generated neurons after SCI. [•] Over-expression of Sox11 promoted neuronal regeneration after SCI. [•] Over-expression of Sox11 increased expression of BDNF after SCI. [•] Sox11 over-expression promoted locomotor recovery after SCI. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0006291X
Volume :
446
Issue :
4
Database :
Academic Search Index
Journal :
Biochemical & Biophysical Research Communications
Publication Type :
Academic Journal
Accession number :
95670670
Full Text :
https://doi.org/10.1016/j.bbrc.2014.02.103