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Stem cells with FGF4-bFGF fused gene enhances the expression of bFGF and improves myocardial repair in rats.
- Source :
-
Biochemical & Biophysical Research Communications . Apr2014, Vol. 447 Issue 1, p145-151. 7p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] BFGF exists only in the cytoplasm of live cells. [•] BFGF cannot be secreted into the extracellular space to promote cell growth. [•] We combine the secretion-promoting signal peptide of FGF4. [•] We successfully modified BMSCs with the fused genes of FGF4-bFGF. [•] We promoted the therapeutic effects of transplanted BMSCs in myocardial infarction. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 447
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 95670622
- Full Text :
- https://doi.org/10.1016/j.bbrc.2014.03.131