Evaluation of Utility of Phenol in Alopecia Areata.

Background: Alopecia areata (AA) is a common hair disorder of unknown etiology and prognosis with no defi nitive cure. Aims and Objective: (i) To study the efficacy and immunomodulatory action of 88% phenol on hair growth on test area in AA. (ii) To study various epidemiological factors in relation to AA. Materials and Methods: A total of 50 subjects presenting with nonscarring patchy hair loss on scalp were enrolled in this prospective open label study to receive 88% phenol at 3 weekly intervals in a tertiary care hospital. Efficacy was assessed using scoring system for density, pigmentation, and texture of growing hair. Results: Texture and pigmentation of hair growth was significantly improved at 9 week, while density of hair growth showed steady improvement, which was signifi cant from 9 week onwards. About 78% of patients showed good to excellent response while none of them showed poor response. Conclusion: 88% phenol was found to be efficacious with all patients showing hair regrowth. 88% phenol can be considered as a treatment of choice for stable AA due to its ease of application, easy availability, and low cost. [ABSTRACT FROM AUTHOR]