Two and three way spectrophotometric-assisted multivariate determination of linezolid in the presence of its alkaline and oxidative degradation products and application to pharmaceutical formulation.

Highlights: [•] Most of reported methods of LIN are based on chromatographic technique. [•] Chromatographic methods are relatively of high cost and consuming time. [•] Multivariate calibration, based on UV spectrophotometric data was used. [•] It is suitable method for an accurate, rapid and less expensive determination. [•] Several methods were simultaneously determine LIN and its degradation products. [Copyright &y& Elsevier]