Study on multilayer structures prepared from heparin and semi-synthetic cellulose sulfates as polyanions and their influence on cellular response.

Highlights: [•] Fabrication of multilayers with three different sulfated polyanions paired with chitosan. [•] Use of semi-synthetic cellulose sulfates as replacement of heparin in multilayers. [•] Study on effects of polyanions chemical composition on layer properties and bioactivity. [•] Distinct differences in multilayer properties and cell behaviour were achieved. [Copyright &y& Elsevier]