Enhanced poly(γ-glutamic acid) fermentation by Bacillus subtilis NX-2 immobilized in an aerobic plant fibrous-bed bioreactor.

Highlights: [•] Aerobic fibrous-bed bioreactor using bagasse as immobilized carrier was designed. [•] The time of immobilization fermentation is 48h while free-cell 72h. [•] PGA yield of 71.21g/L was achieved by repeated fed-batch fermentation in APFB. [•] We evaluated the stability of the APFB system. [•] The changes in the cells of free and immobilized cell fermentation were compared. [ABSTRACT FROM AUTHOR]