Back to Search
Start Over
Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir.
- Source :
-
Virus Research . May2014, Vol. 184, p44-53. 10p. - Publication Year :
- 2014
-
Abstract
- Highlights: [•] Cyclophilin A (CypA) is a host factor for human coronavirus NL63 replication. [•] CypA is a target for anti-coronaviral therapy. [•] Non-immunosuppressive CsA derivatives (Alisporivir, NIM811) inhibit CoV replication. [•] New classes of non-immunosuppressive CsA/FK506 derivatives inhibit CoV replication. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 01681702
- Volume :
- 184
- Database :
- Academic Search Index
- Journal :
- Virus Research
- Publication Type :
- Academic Journal
- Accession number :
- 95627173
- Full Text :
- https://doi.org/10.1016/j.virusres.2014.02.010