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Oral Panax notoginseng Preparation for Coronary Heart Disease: A Systematic Review of Randomized Controlled Trials.
- Source :
-
Evidence-based Complementary & Alternative Medicine (eCAM) . 2013, Vol. 2013, p1-12. 12p. 2 Diagrams, 4 Charts, 1 Graph. - Publication Year :
- 2013
-
Abstract
- This systematic review aims to evaluate current evidence for the benefit and side effect of oral Panax notoginseng preparation for coronary heart disease (CHD). We included 17 randomized clinical trials (17 papers and 1747 participants). Comparing with no intervention on the basis of conventional therapy, oral Panax notoginseng did not show significant effect on reducing cardiovascular events, but it could alleviate angina pectoris (including improving the symptoms of angina pectoris [RR 1.20; 95% CI 1.12 to 1.28; 7 trials, n = 791], improving electrocardiogram [RR 1.35; 95% CI 1.19 to 1.53; 8 trials, n = 727], decreasing the recurrence of angina pectoris [RR 0.38; 95% CI 0.16 to 0.94; 1 trials, n = 60], duration of angina pectoris [RR -1.88; 95% CI -2.08 to -1.69; 2 trials, n = 292], and dosage of nitroglycerin [MD -1.13; 95% CI -1.70 to -0.56; 2 trials, n = 212]); oral Panax notoginseng had no significant difference compared with isosorbide dinitrate on immediate effect for angina pectoris [RR 0.96; 95% CI 0.81 to 1.15; 1 trial, n = 80]. In conclusion, oral Panax notoginseng preparation could relieve angina pectoris related symptoms. However, the small sample size and potential bias of most trials influence the convincingness of this conclusion. More rigorous trials with high quality are needed to give high level of evidence, especially for the potential benefit of cardiovascular events. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ANGINA pectoris
*CONFIDENCE intervals
*CORONARY disease
*DATABASES
*ELECTROCARDIOGRAPHY
*GINSENG
*HERBAL medicine
*INFORMATION storage & retrieval systems
*MEDICAL databases
*CHINESE medicine
*MEDLINE
*META-analysis
*ONLINE information services
*ORAL drug administration
*SYSTEMATIC reviews
*RANDOMIZED controlled trials
*THERAPEUTICS
*PREVENTION
Subjects
Details
- Language :
- English
- ISSN :
- 1741427X
- Volume :
- 2013
- Database :
- Academic Search Index
- Journal :
- Evidence-based Complementary & Alternative Medicine (eCAM)
- Publication Type :
- Academic Journal
- Accession number :
- 95495186
- Full Text :
- https://doi.org/10.1155/2013/940125