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Defective adipose tissue development associated with hepatomegaly in cathepsin E-deficient mice fed a high-fat diet.

Authors :
Kadowaki, Tomoko
Kido, Mizuho A.
Hatakeyama, Junko
Okamoto, Kuniaki
Tsukuba, Takayuki
Yamamoto, Kenji
Source :
Biochemical & Biophysical Research Communications. Mar2014, Vol. 446 Issue 1, p212-217. 6p.
Publication Year :
2014

Abstract

Highlights: [•] Fat-induced cathepsin E-deficient mice display defective adipose tissues. [•] Fat-induced cathepsin E-deficient mice show hepatomegaly with hepatic steatosis. [•] Fat-induced cathepsin E-deficient mice exhibit hypercholesterolemia. [•] In the deficient mice, infiltration of macrophages in adipose tissues is reduced. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0006291X
Volume :
446
Issue :
1
Database :
Academic Search Index
Journal :
Biochemical & Biophysical Research Communications
Publication Type :
Academic Journal
Accession number :
95460298
Full Text :
https://doi.org/10.1016/j.bbrc.2014.02.089