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Globular adiponectin induces a pro-inflammatory response in human astrocytic cells.

Authors :
Wan, Zhongxiao
Mah, Dorrian
Simtchouk, Svetlana
Klegeris, Andis
Little, Jonathan P.
Source :
Biochemical & Biophysical Research Communications. Mar2014, Vol. 446 Issue 1, p37-42. 6p.
Publication Year :
2014

Abstract

Highlights: [•] Adiponectin receptors are expressed in human astrocytes. [•] Globular adiponectin induces secretion of IL-6 and MCP-1 from cultured astrocytes. [•] Adiponectin may play a pro-inflammatory role in astrocytes. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
0006291X
Volume :
446
Issue :
1
Database :
Academic Search Index
Journal :
Biochemical & Biophysical Research Communications
Publication Type :
Academic Journal
Accession number :
95460270
Full Text :
https://doi.org/10.1016/j.bbrc.2014.02.077