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Improved prophylaxis of postoperative nausea vomiting: Palonosetron a novel antiemetic.

Authors :
Shetti, Akshaya N.
Singh, Dewan Roshan
Nag, Kusha
Shetti, Rachita A.
Kumar, V. R. Hemanth
Source :
Anesthesia: Essays & Researches. Jan-Apr2014, Vol. 8 Issue 1, p9-12. 4p.
Publication Year :
2014

Abstract

Many anti-emetics are used in clinical practice. Palonosetron hydrochloride is one of them. It is a novel, centrally acting antiemetic, and anti-nausea agent. This drug is an antagonist of serotonin receptor subtype 3 (5-HT3). This drug has longer duration of action which makes it useful in the prevention and treatment of acute and delayed onset of nausea and vomiting. This drug was initially used for chemotherapy induced nausea and vomiting. Federal drug agency (FDA) has approved it for prevention and treatment of post-operative nausea and vomiting. The literature search for this article was done using Google scholar and Pubmed using the terms ''Palonosetron,'' ''longer duration of action,'' ''nausea,'' ''vomiting,'' and ''postoperative''. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
02591162
Volume :
8
Issue :
1
Database :
Academic Search Index
Journal :
Anesthesia: Essays & Researches
Publication Type :
Academic Journal
Accession number :
95428413
Full Text :
https://doi.org/10.4103/0259-1162.128894