Linkage Analysis of Extremely Discordant and Concordant Sibling Pairs Identifies Quantitative-Trait Loci That Influence Variation in the Human Personality Trait Neuroticism.

Highlights genetic linkage scan that uses extremely discordant and concordant sibling pairs to study quantitative trait loci on chromosomes which influence variation in the personality traits of neuroticism. Use of quantitative genetic analysis of personality to explore relationship between sex and neuroticism; Debatable issues generated by the findings of the research.