Advanced glycation end products, dementia, and diabetes.

Authors :: Lovestone, Simon
Ulf Smith
Source :: Proceedings of the National Academy of Sciences of the United States of America. 4/1/2014, Vol. 111 Issue 13, p4743-4744. 2p.
Publication Year :: 2014
Abstract: The author discusses aspects of advanced glycation end products, diabetes, and dementia. It states that insulin signaling modifies tau phosphorylation in cells and amyloid precursor protein (APP) and in animal models suggest metabolic pathways on canonical pathways of Alzheimer's disease (AD). Furthermore, it notes that age increase the risk of AD.

Subjects :: *DIABETES
*DEMENTIA
*ALZHEIMER'S disease
*AMYLOID beta-protein precursor
*INSULIN
*PHOSPHORYLATION
*ANIMAL models in research

Language :: English
ISSN :: 00278424
Volume :: 111
Issue :: 13
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 95394816
Full Text :: https://doi.org/10.1073/pnas.1402277111