Application of NMR spectroscopy in the development of a biomimetic approach for hydrophobic drug association with physical hydrogels.

Highlights: [•] Hydrophobic drugs are very interesting therapeutic compounds. [•] Their incorporation into accurate drug delivery systems is a technological challenge. [•] A biomimetic approximation was herein developed for this purpose. [•] A novel NMR strategy permitted the characterization of this approximation. [•] This NMR strategy has also great potential for other applications. [Copyright &y& Elsevier]