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Heterodimer formation by retinoid X receptor: Regulation by ligands and by the receptor's self...

Authors :
Dong, Diane
Noy, Noa
Source :
Biochemistry. 07/28/98, Vol. 37 Issue 30, p10691. 10p. 3 Black and White Photographs, 1 Diagram, 2 Charts, 5 Graphs.
Publication Year :
1998

Abstract

Presents a study which examined the implications of tetramer formation by retinoid X receptor (RXR), a nuclear receptor which is activated by 9-cis-retinoic acid (9cRA), for the ability of the receptor to heterodimerize with receptors RAR and VDR. Effects of cognate ligands on heterodimerization of RXR with receptors; Examination of the oligomerization behavior and transcriptional activities of two site specific mutants of mRXR...

Subjects

Subjects :
*TETRAMERS (Oligomers)
*RETINOIDS

Details

Language :
English
ISSN :
00062960
Volume :
37
Issue :
30
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
953836
Full Text :
https://doi.org/10.1021/bi980561r